Idiopathic erythroderma is sometimes called the red man syndrome. Exfoliative dermatitis in a cat veterinary record case. Aug 15, 2019 exfoliative dermatitis is characterized by generalized erythema with scaling or desquamation affecting at least 90% of the body surface area. Exfoliative dermatitis dermatologic disorders merck. Nov 01, 2012 exfoliative dermatitis is an extensive scaling of the skin, frequently associated with pruritus or itching, erythroderma or redness of the skin, and loss of hair. Submit an article journal homepage journal homepage. Disseminated exfoliative dermatitis associated with alltransretinoic acid in the treatment of acute promyelocytic leukemia.
People who are more than 40 years of age have a greater risk of developing this disorder. Erythroderma exfoliative dermatitis is a cutaneous reaction pattern characterized by erythema, edema and scaling of all. The condition has been associated with thymomas but has been described without a thymoma. Generalized exfoliative dermatitis johns hopkins medicine. Exfoliative dermatitis is a rare condition that affects % of the entire population. Exfoliative dermatitis, or erythroderma, is an erythematous, scaly dermatitis involving most, if not all, of the skin. Any age group can be affected, and with most studies excluding children, the average age of disease onset varies from 41 to 61. He was given oral rifampin, 600 mgd in the philippines. Erythroderma is conventionally defined as inflammation of at least 90% of the skin surface, characterized by erythema and variable.
The term exfoliative refers to the exfoliation, or shedding, of the skin. Erythroderma and exfoliative dermatitis springerlink. This article describes a case of feline exfoliative dermatitis with a cranial mediastinal mass suspected to be a thymoma that was seen at the university of illinois veterinary teaching hospital. Specifically, exfoliative toxins ad, which are produced by staphylococcus aureus, specifically cleave the extracellular part of desmoglein 1. Erythroderma is an exfoliative dermatitis that manifests as. It often precedes or is associated with exfoliation skin peeling off in scales or layers, when it may also be known as exfoliative dermatitis ed. Erythroderma exfoliative dermatitis is a cutaneous reaction pattern that can occur in a wide variety of benign and. Erythema multiforme em, stevensjohnson syndrome sjs and toxic epidermal necrolysis ten are the main clinical presentations of drug induced ed.
Exfoliative dermatitis, generalized redness and scaling of the skin that usually arises as a complication of a preexisting skin disease or of an allergy. Erythroderma or exfoliative dermatitis is any inflammatory skin disease that affects more than 90% of the body surface. Download as ppt, pdf, txt or read online from scribd. Venereology skinvd centre, sehgal nursing home, panchwati, azadpur, delhi, skin institute and school of dermatology, greater kailash, new delhi, and department of dermatology and std, lady hardinge medical college, new delhi, india. Exfoliative dermatitis is widespread erythema and scaling of the skin caused by preexisting skin disorders, drugs, cancer, or unknown causes. General exfoliative dermatitis pityriasis rubra remarks introductory to a debate on this subject at a special meeting of the dermatological society of london, on the 9th november, 1898, mr. Generalized exfoliative dermatitis, or erythroderma, is a severe inflammation of the entire skin surface. It is presented by redness and scaling of the skin that begins in the patches and spreads to the whole body. It is known to affect people of all races and countries.
Comments on current literature ritters disease exfoliative dermatitis of the newborn i n 18 7 8 ritter1 of prague described. An underlying systemic disease is an important contributing factor as well. The extent of the skin changes can obscure the primary lesion making it difficult to. Exfoliative dermatitis is usually caused by preexisting skin disease, especially psoriasis, atopic dermatitis, severe seborrheic dermatitis, drug hypersensitivity to a variety of antibiotics, anticonvulsants, and antiinflammatory agents, and underlying leukemia, lymphoma, or visceral malignancy. Exfoliative dermatitis is peeling of the skin over large areas of the body. It is presented by redness and scaling of the skin that. Aug 22, 2016 drug induced exfoliative dermatitis ed are a group of rare and severe drug hypersensitivity reactions dhr involving skin and usually occurring from days to several weeks after drug exposure. Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree.
Exfoliative dermatitis is an inflammatory dermatosis involving more than 90% of. Exfoliative dermatitis msd manual professional edition. If untreated, erythroderma can be fatal because of its metabolic. In about one fifth of the patients the exfoliative dermatitis was. Factitial cheilitis is a rare diagnosis of exclusion that occurs most frequently in young women with a history of anxiety disorders and recent psychosocial stressors. Your doctor works to correct any dehydration, low blood volume, heat loss, and electrolyte or nutritional deficiencies. Thirteen patients were clearly exhibiting nose sign, ie, sparing of the nose and the paranasal area. The most common causes of death in patients with exfoliative dermatitis are pneumonia, septicemia, and heart failure. Pdf drug induced exfoliative dermatitis ed are a group of rare and severe drug hypersensitivity reactions dhr involving skin and. Drug induced exfoliative dermatitis ed are a group of rare and severe drug hypersensitivity reactions dhr involving skin and usually occurring from days to several weeks after drug exposure. More rarely, it may be indicative of a systemic disease, such as cancer of the lymphoid tissue. Download dermatitis, exfoliative download free online book chm pdf.
Exfoliative dermatitis definition of exfoliative dermatitis. Exfoliative dermatitis is the severe inflammatory condition of the entire skin surface due to reaction to certain drug or due to preexisting skin condition which leads to this condition. What is exfoliative dermatitis and how to deal with it. Exfoliative definition of exfoliative by the free dictionary.
Exfoliative dermatitis causes treatment dr thind homeopathy. A study of 46 cases of exfoliative dermatitis revealed peak distribution in sixth decade and very high. A prospective study in 80 exfoliative dermatitis patients over a period of 5 years establishes 41. Exfoliative dermatitis is characterized by generalized erythema with scaling or desquamation affecting at least 90% of the body surface area. Download the pdf to view the article, as well as its associated figures and tables. As an extension of our researches into exfoliative dermatitis, we decided to investigate some asjects of vitamin cmetabolism in this condition. If you have problems viewing pdf files, download the latest version of adobe reader. There is continuous production and desquamation shedding of thick, brown scales of keratin.
Several large studies have reported a widely varied incidence of exfoliative dermatitis ed ranging from 0. Exfoliative dermatitis is a condition which causes exfoliation and redness of the skin. Find highquality stock photos that you wont find anywhere else. Certain lymphomas cancers of the lymph nodes and other cancers, such as leukemia, may also cause exfoliative dermatitis. Visit our research pages for current research about exfoliative dermatitis treatments clinical trials for exfoliative dermatitis. Dapsone induced exfoliative dermatitis nepal journals online.
Read more about symptoms, diagnosis, treatment, complications, causes and prognosis. Exfoliative dermatitis is a skin disorder with inflammation and scaling of skin, most often on the entire skin. Systemic and potentially lifethreatening complications include fluid and electrolyte imbalance, thermoregulatory disturbance, fever, tachycardia, highoutput failure, hypoalbuminemia, and septicemia. Pityriasis rubra pilaris prp is a chronic generalized exfoliative dermatitis sloughing skin characterized by erythema redness, scaling, dilated plugged hair follicles, and keratoderma thickened skin of the hands and feet that is often associated exfoliative dermatitis diffuse skin involvement. Erythroderma is a term used to describe erythema affecting more than 90% of the body surface. For language access assistance, contact the ncats public information officer. Exfoliative dermatitis merck manuals consumer version. The disease affected both males and females, with a. This is due to a reaction to certain medicines, a preexisting skin condition, and sometimes cancer.
Erythroderma or exfoliative dermatitis is caused by various diseases including eczema of various subtypes, psoriasis, lymphoma, leukaemia, pemphigus foliaceus, lichen planus, dermatophytosis, crusted scabies, drugs including phenylbutazone, phenytoin, carbamazepine, gold salts, lithium, cimetidine, hereditary disorder like ichthyosiform erythroderma and pityriasis rubra pilaris also can lead. It is characterized by redness and scaling of the skin that begins in. Treatment involves corticosteroids and correction of the. The most common cause of erythroderma is exacerbation of an underlying skin disease, such as psoriasis, contact dermatitis, seborrheic dermatitis, lichen planus, pityriasis rubra pilaris or a drug reaction, such as the use of topical steroids. This leads to bullous impetigo and staphylococcal scalded skin syndrome with superficial blistering in the epidermis, findings that are histologically similar to pemphigus foliaceus associated with auto. Search from 60 top exfoliative dermatitis pictures and royaltyfree images from istock.
Exfoliative dermatitis pictures, images and stock photos. You may receive treatment for exfoliative dermatitis in the hospital. Sep 18, 2012 exfoliative dermatitis is a skin disorder with inflammation and scaling of skin, most often on the entire skin. Exfoliative dermatitis symptoms, diagnosis, treatments and. Erythroderma is generalized exfoliative dermatitis, which involves 90% or more of the patients skin. Find a list of current medications, their possible side effects, dosage, and efficacy when used to treat or reduce the symptoms of. Dermatitis herpetiformis has a histopathologic appearance similar to linear iga disease, except that the basement membrane deposits of iga have a more irregular or granular appearance. Among 5 patients with exfoliative dermatitis, the most common causative factors were drugs and preexisting dermatoses. Affected areas can progress to superinfection with staphylococcus aureus or candida albicans.
By and large, most cases involve a preexisting skin disease. Instances of idiopathic exfoliative dermatitis probably represent examples in which the cause was overlooked. Exfoliative dermatitis tends to involve most, if not all, of the skin. More detailed information about the symptoms, causes, and treatments of exfoliative dermatitis is available below. Treatment involves corticosteroids and correction of the cause. Exfoliative dermatitis, also known as erythroderma, is an uncommon but serious skin disorder that family physicians must be able to recognize. A 63yearold filipino man had evidence of pulmonary tuberculosis on routine chest radiographic examination in october 1986. Cureus exfoliative cheilitis as a manifestation of. Among 5 patients with exfoliative dermatitis, the most common causative factors. Looking for medication to treat exfoliative dermatitis.
We report a case of exfoliative dermatitis we believe was induced by rifampin. Rifampin and exfoliative dermatitis annals of internal. Symptoms include redness of skin, there may be severe itching and skin becomes thick and swollen lymph nodes. Exfoliative dermatitis skin disorders msd manual consumer. Exfoliative dermatitis, also known as erythroderma, is an uncommon but serious skin disorder that family physicians must be able to recognize and treat appropriately. Bullous dermatitis an overview sciencedirect topics. Manual of histologic staining methods of the armed forces. Comments on current literature ritters disease exfoliative dermatitis of the newborn i n 18 7 8 ritter1 of prague described an exfoliative dermatitis in newborn infants. Exfoliative dermatitis is known to develop in people having severe cases of psoriasis or eczema. The term exfoliative dermatitis is also used, and describes the exfoliation skin peeling found in erythroderma. What is erythroderma erythroderma is the term used to describe intense and usually widespread reddening of the skin due to inflammatory skin disease. Symptoms and signs are pruritus, diffuse erythema, and epidermal sloughing.
In some cases, it is a complication of other skin diseases, such as atopic dermatitis, psoriasis, and contact dermatitis. Exfoliative dermatitis ed is defined as diffuse erythema and scaling of the skin involving more than 90% of the total body skin surface area. It presents as continuous keratinaceous buildup, crusting, and desquamation of the lips, consistent with exfoliative cheilitis. Exfoliative dermatitis article about exfoliative dermatitis. He considered the disease to be septic, a mani festation of pyemia, and reported 297 cases in newborn.
Abstract the object in reporting this case, which might be termed dermatitis exfoliativa prenatal rather than neonatal, is to call attention to the undoubted development of this disease, or condition in utero. Diffuse exfoliative rash with sepsis and eosinophilia. Compare current exfoliative dermatitis drugs and medications. Background exfoliative dermatitis is a cutaneous syndrome characterized by generalized exfoliation and erythema, which may be result from or be. In approximately 25% of people, there is no identifiable cause. Exfoliative dermatitis causes, symptoms, risk factors. Exfoliative dermatitis or erythroderma is a skin condition where the skin becomes reddened and inflamed accompanied by severe itching and peeling of the skin. Possible causes include other underlying skin conditions, medications, malignancy or undeterminable factors. Feline exfoliative dermatitis is a rare skin disorder that is characterised by diffuse scaling and alopecia.
963 461 1334 905 248 27 321 857 538 377 1234 1521 332 395 142 791 1081 464 1264 317 1034 1449 440 145 724 1025 44 703 262 949 1215 1234 433